Not necessarily.
Fevers can cause seizures and they can have detrimental effects in paediatric patients. For the bulk of the general population, these painkillers/anti inflammatories are simply symptom relief.
For those talking about hyperthermia killing, yes but in almost all those cases the cause is not an infection.
In fact, I would say that paracetamol kills a hell of a lot more patients than it actually ‘saves’.
A study I have taken to heart is that permissive hyperthermia (up to 40 deg c) in ICU patients has a greater survival than those where fever is treated aggressively.
Physiologically, this resonates because high temperatures activate the immune system and raised temperatures are non-optimal for bacterial proliferation; so the immune system is primed by fever; suppressing it can dull immune system response.
In fact, malaria was used as a treatment for syphillis in the early parts of the 20th century because high temperatures kill spirochetes. There are also a decent number of case reports of cancers going into remission following fever.
However in my quick mobile google then I could only see the following study that demonstrated no advantage for either control of permissive hyperthermia group in ICU patients; so perhaps I was relying on a study that has been superceeded.
Fever can indeed kill. Raise the body temp a few degrees, no matter the cause, and things start going wrong very quickly. Google hyperthermia.
In fact, i cannot think of any disease that literally kills. Even with the big stuff like cancer or aids, it is always the symptoms that get you. They damage body systems and the decline of those systems (aka symptoms) eventually causes the cardiac arrest or internal bleeds that shut off nutrients to the brain. Those symptoms are just as lethal no matter thier cause. A massive fever that stops normal body chemistry, whether caused by flu or ebola, will kill you just the same.
Yes but the extra heat in the body causes the same cascade of chemical changes that will eventually kill. Initial treatment is different, to a point. If a fever is too high it will suddenly need the same treatment as hyperthermia: direct cooling.
Not a doctor: Isn’t fever (objectively, it seems) defined as a rise in body temperature? From what I’ve learned about protein denaturalization in high school, that doesn’t sound good if excessive.
And an acetaminophen tablet is a painkiller. While your statement is in fact true, ibuprofen is still a better choice for a fever. The latter is also generally considered a safer alternative, especially in long-term use — even though alternating the two would be ideal.
Acetaminophen is actually a pretty dangerous drug that is pretty easy to overdose on. It’s been said if it were discovered today it would be a prescription drug.
On top of that numerous recent studies have shown many potential problems.
> Heavy use of acetaminophen is associated with kidney disease and bleeding in the digestive tract, the paper reports. The medication also has been linked to increased risk of heart attack, stroke and high blood pressure, the study authors noted.
> One cited study even showed that overuse of acetaminophen can increase a person's risk of early death as much as 60 percent, the study authors found.
1. They already have such offering (VS Team Services).
2. Their competitors (GitLab, Bitbucket) already have that offering.
3. I don't think they're interested in GitHub for its revenue, but for its strategic value. GitHub has to protect its revenue model by disallowing free private repos, Microsoft can afford to be more flexible.
4. They've already made similar moves. They acquired Xamarin, which was expensive, and made it free.
While you don't believe you are locked in, I don't believe that you as a programmer "power user" are the majority that Apple cares about.
I believe not only that for the majority of users there is a level of software lock-in, but further there is a high level of psychological lock-in, where users get used to and comfortable with Apple's design strength, which is Apple's main offering.
As people get more comfortable and more older it is easy to say that people get more resistant to change.
Many people here mention "parenting" as a solution to this problem, and although this is a solution available to the wealthy and time wealthy audience of hacker news, the other side of the world, probably in your own country and certainly in poorer countries, the people aren't able to put in as much attention into monitoring their children or to put in time understanding the many harms of the modern world.
The real problem is the mass effect of these people. The majority of the world.
We all like to think we are above manipulation, maybe as a form of egoism, but in reality we are all simple creatures compared to the momentum of science.
I never could understand why people have such a hard time admitting that a literal TEAM of PhD owning Psychologists who have spent their entire lives designing ways to trick and manipulate you could possibly be successful. That'd be like saying Ford couldn't possibly build an engine better than the one you hacked together from plumbing parts, just because you can't fathom the concept of people being good at their jobs
If you like the combination of Jade + CoffeeScript + LESS, then I submit my generator for your consideration (and I would appreciate any insights you may have on its shortcomings or possible improvements). My generator is slightly more barebones than webapp:app. I don't include LiveReload, connect or require.js initially:
- I did not need LiveReload or connect because I use a combination of `grunt watch` and `http-server -c-1`[1] during development with no issues.
- require.js has not been an immediate requirement for me across a lot of projects, so I decided to defer the decision to the developer and go with a minimal setup.
The inbuilt webapp generator makes no decisions on which template language to use (some may prefer this over starting with Jade). It also decides to go with SASS/Compass instead of LESS. This is also fine except that it means I now need to have ruby and compass installed which I wanted to avoid[2].
The way I approach asset revving is a bit different in that I pass the developer a function to use in their Jade templates to refer to assets (images/css/etc...). It will resolve the path to an asset and form the url with a revision appended as a request parameter during template compilation (not after). It is kind of similar to the way django_compressor does its job if you are familiar with it (that was my primary inspiration).
Finally, I intend to improve the Gruntfile further by defining concurrent tasks, adding a clean task and so on.
They appear to block all popups except those caused by a direct click by the user. I think that's why some websites spam popup windows when you make your first click.
It is an issue where you object to a certain subset of language, language that is used to express strong or passionate feelings about things. I have never given swearing much thought and I don't understand what makes you object to it.
I guess I have always felt that the less people have to sensor themselves them better.
The wikipedia article on the subject [http://en.wikipedia.org/wiki/Profanity] is not as informative as I'd hoped.
It might be better to use variations in the background color. It may feel more natural to do so and it would allow normal syntax highlighting alongside scope highlighting.
I was just thinking the same; when all my syntax highlighting in a region looks backwards, I normally assume I've got a mismatched quote just before it. I think I'd be thinking that with this all the time.
Subtle changes in the background colour would be a nice alternative.
Make the background color become less contrasting with the foreground color the more you nest.
The larger the number of nested scopes, the harder it's going to be to read it anyway!
