Don't worry too much, each person is different. I am WFH'ing for a good several years now, and largely enjoy it. Also, I believe, in my case pros outweigh the cons.

Lucky to have a family, which does help a great deal in this situation. But, I do sometimes worry about it, but as a result compensate for it - exercising to stay fit/lean. Also, always try to be on the cutting edge of tech - HN/similar is great for that.

Edit: Just to add two more points:

1) Social networks: One might think, that they will help in this situation. But again, its different for everyone. I find, in my case their use is detrimental. So after having disconnected from them totally (save a pseudonymous twitter a/c for news/venting), I find it more peaceful, also I found my friendship with good friends has improved. And Facebook friends withered off.

2) Another thing, I learnt a few years ago, some people need social interactions to re-energize where as for some people it is solitude. Are you the type, who if goes for a walk in the park, and when people try to hold a long conversation, do you like it? Or would you rather be left alone after greeting/short-conversations. I definitely, am the second type. (If I am portraying my personality to be totally anti-social, then that's inaccurate. As my social needs are fulfilled well, by family and friends. May be if I had less of that, then would definitely like to have long talks with strangers in the park. Each person has different situation and needs, that's the key point).

Having done musical theater as my main hobby for almost 8 years I can thoroughly recommend it for that exact purpose. There's something about singing with folks and sharing a stage that leads very quickly to strong deep social bonds. It's also a nice contrast to my tech friends I find.