You can use any distro you like. I'm using OpenSUSE Tumbleweed and have basically the same experience as most people on ProtonDB. The thing to remember is that to use Proton for games that Valve hasn't verified, you have to go into your Steam settings and under Steam Play check "Enable Steam Play for all other titles".
I have noticed that some games work better or worse under different versions of Proton, though.
I have noticed that some games work better or worse under different versions of Proton, though.